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Glypican 3, IHC without Interpretation

Test Code
90212


CPT Codes
88342

Preferred Specimen
Formalin-fixed paraffin-embedded tissue block submitted in an IHC specimen transport kit


Other Acceptable Specimens
3 unstained, (+) positively charged slides


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable


Methodology
Immunohistochemistry (IHC)

Setup Schedule
Set up: Mon-Fri; Report available: Next day


Clinical Significance
Glypican 3 (GPC3) is most commonly used in the differential diagnosis of hepatocellular carcinoma (HCC) or hepatoblastoma, which overexpress GPC3 compared to cirrhotic liver or other non-neoplastic liver lesions. Embryonal germ cell tumor and Wilms tumor also overexpress glypican 3.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.