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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
First Trimester Screen, Hyperglycosylated hCG (h-hCG) (NY)
Test Code16969
CPT Codes
81508<br /> This code is for New York State clients only. For Non-New York State patient testing, use code 16020
Includes
PAPP-A (Pregnancy-associated Plasma Protein), h-hCG (hyperglycosylated hCG), risk calculation which includes NT (Nuchal Translucency)
Preferred Specimen
1.5 mL serum
Minimum Volume
0.8 mL
Instructions
This test cannot be performed unless all demographic data and test data (e.g., nuchal translucency [NT] measurement) are provided by the ordering physician.
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 28 days
Refrigerated: 14 days
Frozen: 28 days
Methodology
Chemiluminescence (CL) • Immunoassay (IA)
FDA Status
PAPP-A: This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.
Setup Schedule
Set up: Mon-Sat; Report available: 4-6 days
Limitations
First Trimester Screen results consistent with increased risk of trisomy should be confirmed with CVS or amniotic fluid specimen. Maternal serum screening yields a low percentage of false negatives. A wide range of other chromosomal abnormalities are not identified by maternal serum screening.
Reference Range
MSS Down Syndrome Risk | <1:270 |
MSS Risk for Trisomy 18 Risk | <1.100 |
Clinical Significance
To screen for Down syndrome and trisomy 18 at 9.0-13.9 weeks gestation.