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Everolimus, LC/MS/MS, Blood
Test Code18883
CPT Codes
80169
Preferred Specimen
2 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
1 mL
Instructions
Drug regimens are to be noted on requisition: Time and date of drug administration.
Note: Therapeutic range applies to trough specimens drawn just prior to a.m. dose.
Note: Therapeutic range applies to trough specimens drawn just prior to a.m. dose.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gel barrier tubes • Clotted specimens
Methodology
Chromatography/Mass Spectrometry
Setup Schedule
Set up: Mon-Sat; Report available: Next day
Reference Range
Trough | 3.0-8.0 ng/mL for Transplantation |
Trough | 5.0-10.0 ng/mL for Oncology/Neurology |
Clinical Significance
Everolimus is an immunosuppresive drug used in organ transplantation to prevent graft rejection. Therapeutic drug monitoring is useful to optimize dose and avoid toxicity.