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Profilin (t216) IgE
Test Code39153
CPT Codes
86008
Preferred Specimen
0.5 mL serum
Minimum Volume
0.3 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Sat; Report available: 1 day
Reference Range
<0.10 kU/L
Clinical Significance
Profilins are found in pollens from trees, grasses, weeds, fruits, vegetables, nuts, spices, and latex. IgE reactivity to profilins contributes significantly to IgE cross-reactivity between trees, grasses, and weeds. Since profilins are also known to be heat and protease sensitive, profilin specific IgE is an important trigger for oral allergy syndrome: A mild, short lived, oral reaction, occurring immediately after the ingestion of raw fruits, vegetables, and nuts. This syndrome is more commonly seen in pollen allergic patients than in patients with true food allergies.