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Creatinine, Random Urine [8459X]
Test Code6027
CPT Codes
82570
Preferred Specimen
10 mL of a random, unpreserved urine collected in a plastic urine container
Minimum Volume
0.5 mL
Other Acceptable Specimens
Urine collected in urinalysis transport tube (yellow-top, blue fill line, preservative tube) • Preserved urine with 6N HCl acid submitted in a plastic, urine container
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Methodology
Colorimetric (C) • Kinetic
Setup Schedule
Set up: Daily; Report available: 1-3 days
Reference Range
≤6 Months | 2-28 mg/dL | |
7-11 Months | 2-31 mg/dL | |
1-2 Years | 2-110 mg/dL | |
3-8 Years | 2-130 mg/dL | |
9-12 Years | 2-160 mg/dL | |
>12 Years Male | 20-320 mg/dL | |
>12 Years Female | 20-275 mg/dL |
Clinical Significance
Creatinine is the endproduct of creatinine metabolism. Creatinine is present primarily in muscle and the amount of creatinine produced is related to total skeletal muscle mass. Daily creatinine production is fairly constant except when there is a massive injury to muscle. The kidneys excrete creatinine very efficiently and blood levels and daily urinary excretion of creatinine fluctuate very little in healthy normal people. Since blood and daily urine excretion of creatinine show minimal fluctuation, creatinine excretion is useful in determining whether 24-hour urine specimens for other analysis (e.g., Protein) have been completely and accurately collected.