Cortisol, Free, LC/MS/MS, Second Void Urine

Test Code

90582

CPT Codes
82530, 82570

Includes

Creatinine, Random Urine

Preferred Specimen

2 mL of an unpreserved random urine (second a.m. urine) submitted in a plastic leak-proof container

Minimum Volume

0.5 mL

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature

Methodology
Colorimetric (C) • Kinetic • Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon-Fri nights; Report available: 4-6 days

Reference Range

Cortisol,Free,2nd Void Urine

3.5-87.1 mcg/g creat

Creatinine, Random Urine

≤6 Months	2-28 mg/dL
7-11 Months	2-31 mg/dL
1-2 Years	2-110 mg/dL
3-8 Years	2-130 mg/dL
9-12 Years	2-160 mg/dL
>12 Years Male	20-320 mg/dL
>12 Years Female	20-275 mg/dL

Clinical Significance

Urinary free cortisol is useful in the detection of patients with Cushing's syndrome for whom free cortisol concentrations are elevated.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.