Copper, Random Urine

Test Code

15319

CPT Codes
82525, 82570

Includes

Creatinine

Preferred Specimen

7 mL random urine collected in an acid-washed or metal-free container

Minimum Volume

3 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature; 5 days
Refrigerated: 7 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Fecal contamination

Methodology
Inductively Coupled Plasma/Mass Spectrometry (ICP/MS) or Atomic Spectroscopy (AS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Daily p.m.; Report available: Next day

Reference Range

Copper, Random Urine

<87 mcg/g creatinine

Creatinine, Random Urine

≤6 Months	2-28 mg/dL
7-11 Months	2-31 mg/dL
1-2 Years	2-110 mg/dL
3-8 Years	2-130 mg/dL
9-12 Years	2-160 mg/dL
>12 Years Male	20-320 mg/dL
>12 Years Female	20-275 mg/dL

Clinical Significance

Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is disturbed in Wilson's disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Urinary copper concentrations are also useful to monitor patients on chelation therapy.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.