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CK14, IHC with Interpretation
Test Code90154
CPT Codes
88342
Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block
Other Acceptable Specimens
Minimum: 3 unstained slides, positively charged
Instructions
Please include surgical pathology report.
Transport Container
IHC Specimen Transport Kit
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable
Refrigerated: Indefinitely
Frozen: Unacceptable
Methodology
Immunohistochemistry
Setup Schedule
Set up: Mon-Fri a.m.; Report available: 3 days
Reference Range
Interpretive report
Clinical Significance
CK14, a marker of squamous and basal epithelial phenotype, is most frequently used along with CK5/6 and P63 to diagnose the basal subset of breast carcinoma. CK14 expression is also characteristic of oncocytic tumors at various tissue sites and can be used to differentiate these tumors from other epithelioid neoplasms, such as conventional renal cell carcinoma.