CEA with HAMA Treatment

Test Code
15018


CPT Codes
82378 (x2)

Preferred Specimen
2 mL serum


Minimum Volume
1 mL


Transport Container
Plastic screw-cap vial


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days


Methodology
Immunoassay (IA)

Setup Schedule
Set up: Tues, Thurs, Sat; Report available: 2-3 days


Limitations
Approximately 5% of colorectal cancers are not associated with increased levels of CEA.  CEA may be elevated in many types of solid cancer.


Reference Range
CEA, HAMA Treated See below
CEA, Untreated  
  Non-smoker <2.5 ng/mL
  Smoker <5.0 ng/mL


Clinical Significance
CEA is a tumor marker that is useful to monitor patients with persistent, recurrent or metastatic colonic carcinoma. Patients who have received mouse monoclonal antibodies as part of treatment should have their specimens pre-treated for removal of the human antimouse antibodies (HAMA).




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.