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Clinical Trial Methemoglobin
Test Code9647
CPT Codes
83050<br>Clinical Trial Code
Preferred Specimen
5 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
0.5 mL
Instructions
Specimen MUST be delivered refrigerated within 72 hours of collection for analysis.
Please note: Heparinized or citrated whole blood can also be used IF client provides a hemoglobin result on the patient.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 2 hours
Refrigerated: 72 hours
Frozen: Unacceptable
Refrigerated: 72 hours
Frozen: Unacceptable
Methodology
Spectrophotometry
Setup Schedule
Set up: Daily; Report available: 1 day
Reference Range
See Laboratory Report
Clinical Significance
The Methemoglobin concentration in blood is increased to 10 to 30 percent of the total hemoglobin in congenital methemoglobinemia. Methemoglobin is increased to some degree in persons who have ingested nitrites, nitrates, or certain drugs or chemicals such as phenacetin, phenazopyridine, sulfonamides, sulfones, or aniline dyes, as well as in those who have received a local anesthetic that contains an aniline ring, such as benzocaine or lidocaine.