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LGI1 Autoantibody Test (Epilepsy)
Test Code92829
CPT Codes
86255<br>Limited Access Code
Preferred Specimen
2 mL serum
Minimum Volume
0.5 mL
Other Acceptable Specimens
2 mL CSF submitted in a sterile, leak-proof container
Instructions
Serum must be separated from whole blood within 48 hours of collection.
Notes: Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.
Notes: Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 72 hours
Refrigerated: 28 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis; Grossly lipemic; Grossly icteric; Turbid; Bacterial contamination
Methodology
Immunofluorescence Assay
FDA Status
This test was developed and its analytical performance characteristics have been determined by Athena Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Sun, Tues, Thurs; Report available: 5-7 days
Reference Range
Positive/negative for LGI1
Clinical Significance
Anti-LGI1 antibody is found in patients with associated with epilepsy of acute/subacute presentation without evidence of CNS infection, toxic, metabolic, or other known cause of epilepsy, and possibly with evidence of CNS inflammation.
