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Amikacin, Trough
Test Code8583
CPT Codes
80150
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Patient Preparation
Collect as a trough just prior to next dose
Minimum Volume
0.2 mL
Other Acceptable Specimens
Plasma collected in: Fluoride oxalate (gray-top) tube or EDTA (lavender-top) tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 7 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube (SST) • Heparin plasma
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Sat; Report available: 1-2 days
Reference Range
4.0-8.0 mg/L
Clinical Significance
Amikacin is an aminoglycoside antibiotic used in the treatment of gram-negative bacillary infections. Amikacin is potentially nephrotoxic and ototoxic and serial monitoring of serum levels provides information to maintain safe and therapeutic levels.
