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ANA Screen, IFA, with Reflex to Titer and Pattern
Test Code901649
CPT Codes
86038<br>Restricted Client Code
Includes
This is a client specific reflex test. Reflex criteria has been pre-defined by the ordering physician. Additional testing will be performed at an additional charge.
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Microbial contamination may interfere
Methodology
Immunofluorescence Assay (IFA)
Setup Schedule
Set up: Mon-Sat; Report available: Next day
Reference Range
| ANA Screen, IFA | Negative |
| ANA Titer | |
| <1:40 | Negative |
| 1:40-1:80 | Low antibody level |
| >1:80 | Elevated antibody level |
Clinical Significance
Antinuclear antibodies are associated with rheumatic diseases including Systemic Lupus Erythematous (SLE), mixed connective tissue disease, Sjogren's syndrome, scleroderma, polymyositis, CREST syndrome, and neurologic SLE.
