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(CTC) HPV Genotypes 16 and 18, Cervical (ThinPrep)
Test Code70620
CPT Codes
87625<br>Clinical Trial Code
Preferred Specimen
ThinPrep®: 3 mL of PreservCyt® fluid
Minimum Volume
1.5 mL
Instructions
Collect the sample as usual according to the manufacturer?s instructions.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 6 months
Refrigerated: 6 months
Frozen: Unacceptable
Refrigerated: 6 months
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Cervical swabs in Digene® HC cervical sampler; SurePath™ vial without cervical brush/broom; Swabs; SurePath™ pellet; Samples treated with Acetic Acid; Vaginal sources
Methodology
Real-Time PCR
Setup Schedule
Set up: Tues-Sat; Report available: Next day
Clinical Significance
Persistent infection with high-risk HPV types increases a woman's risk for progression to dysplasia or cervical cancer. The rate of progression or degree of risk depends on the HPV type. Of all various high-risk types, HPV Types 16 and 18 cause more than 60-65% of cervical cancers. This test will identify the presence or absence of HPV Type 16 DNA and /or Type 18 DNA. Knowledge of the HPV genotype will help physicians diagnose the type of HPV infection and its risk of developing into dysplasia or cervical cancer.