HPV Genotypes 16 and 18, Cervical (SurePath)

Test Code

70619

CPT Codes
87625<br>Clinical Trial Code

Preferred Specimen

SurePath™: 2 mL of SurePath™ fluid

Minimum Volume

1 mL

Instructions

Collect the sample as usual according to the manufacturer's instructions.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 28 days
Refrigerated: 6 months
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Cervical swabs in Digene® HC cervical sampler • SurePath™ vial without cervical brush/broom • Swabs • SurePath™ pellet • Samples treated with Acetic Acid • Vaginal sources

Methodology
Real-Time PCR

Setup Schedule

Set up: Tues-Sat; Report available: Next day

Clinical Significance

Persistent infection with high-risk HPV types increases a woman's risk for progression to dysplasia or cervical cancer. The rate of progression or degree of risk depends on the HPV type. Of all various high-risk types, HPV Types 16 and 18 cause more than 60-65% of cervical cancers. This test will identify the presence or absence of HPV Type 16 DNA and /or Type 18 DNA. Knowledge of the HPV genotype will help physicians diagnose the type of HPV infection and its risk of developing into dysplasia or cervical cancer.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.