Sterols, Plasma

Test Code

39329

CPT Codes
82542<br /> Restricted Client Code

Preferred Specimen

0.5 mL plasma collected in a sodium heparin (green-top) tube

Minimum Volume

0.2 mL

Other Acceptable Specimens

Plasma collected in an EDTA (lavender-top) tube, or ACD solution (yellow-top) tube, or PPT EDTA (white-top) tube

Instructions

Centrifuge specimen and aliquot plasma into plastic vial. Send plasma frozen

Transport Temperature

Frozen

Specimen Stability

Room temperature: 14 days
Refrigerated: 28 days
Frozen: 92 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Gross lipemia • Gross icterus

Methodology
Gas Chromatography Mass Spectrometry

FDA Status
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Setup Schedule

Set up: Tues, Fri; Report available: 3 days

Reference Range

7-Dehydrocholesterol: < or = 2.0 mg/L
8-Dehydrocholesterol: < or = 0.3 mg/L
8(9)-Cholestenol: < or = 5.0 mg/L
Campesterol: < or = 8.0 mg/L
Cholestanol: < or = 6.0 mg/L
Desmosterol: < or = 2.5 mg/L
DiHydro T-MAS: < or = 0.3 mg/L
Lathosterol: < or = 6.0 mg/L
Sitosterol: < or = 15.0 mg/L
Squalene: < or = 1.0 mg/L
Stigmasterol: < or = 0.5 mg/L

Clinical Significance

Investigation of possible desmosterolosis (desmosterol reductase deficiency), cerebrotendinous xanthomatosis, lathosterolosis, and sitosterolemia

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.