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CCP Antibodies IgG/IgA
Test Code37649
CPT Codes
86200<br /> Limited Access Code
Preferred Specimen
1 mL serum
Minimum Volume
0.3 mL
Instructions
Following collection, serum should be separated from the clot.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 14 days
Refrigerated: 14 days
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia • Gross bacterial contamination • Addition of azide or other preservative • Heat inactivation
Methodology
Enzyme Linked Immunosorbent Assay (ELISA)
Setup Schedule
Set up: Daily; Report available: 1 day
Reference Range
See Laboratory Report
Clinical Significance
The presence of CCP antibodies, when considered in conjunction with other laboratory and clinical findings, is an aid in the diagnosis of rheumatoid arthritis (RA). Approximately 70% of RA patients are positive for anti-CCP IgG, while only 2% of random blood donors and control subjects are positive.