Fibrinogen Activity, Clauss

Test Code

30380

CPT Codes
85384<br /> Limited Access Code

Preferred Specimen

1 mL platelet-poor plasma collected in 3.8% sodium citrate (light blue-top) tube

Minimum Volume

0.5 mL plasma

Other Acceptable Specimens

4.5 mL whole blood collected in 3.8% sodium citrate (light blue-top) tube

Instructions

Please submit a separate, frozen vial for each special coagulation assay ordered.

Platelet Poor Plasma: Centrifuge light blue-top tube 15 minutes at approx. 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL) Freeze immediately and ship on dry ice.

Transport Container

Plastic vial

Transport Temperature

Plasma: Frozen
Whole blood: Room temperature

Specimen Stability

Plasma
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days

Whole blood
Room temperature: 24 hours
Refrigerated: 24 hours
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis and clotted specimens are unacceptable

Methodology
Clot Detection, Clauss

Setup Schedule

Set up: Mon-Sat; Report available: Next day

Reference Range

175-425 mg/dL

Clinical Significance

Fibrinogen is essential for the formation of a blood clot. Deficiency can produce mild to severe bleeding disorders.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.