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Menorrhagia Screen (without Consultation) [19649X]
Test Code1838150
CPT Codes
85240, 85245, 85246, 85270, 85610, 85730
Includes
Activated Partial Thromboplastin Time; Prothrombin Time with INR; Factor XI Activity; von Willebrand Factor Antigen; Ristocetin Cofactor Activity; Factor VIII Activity
Preferred Specimen
1 mL platelet-poor plasma collected in (x3) 3.2% sodium citrate (light blue-top) tubes
Minimum Volume
1 mL (x2)
Instructions
Collect blood in 3 sodium citrate tubes (blue-top); tubes must be filled to capacity to insure correct blood to anticoagulant ratio. Centrifuge whole blood at 1500g for 15 minutes. Avoiding the buffy coat, transfer plasma, using a plastic pipette, into a new plastic tube and repeat centrifugation. Aliquot plasma using a plastic pipette into 3 new plastic vials and freeze.
For preparation of platelet poor plasma and calculations for the collection of sodium citrate tubes from individuals with elevated Hct, refer to Quest Diagnostics Nichols Institute Directory of Services under Specimen Collection section, Coagulation Testing, for further information on specimen processing.
Specimens must remain frozen during storage and shipment. All requests for coagulation assays should include a brief patient history and other pertinent clinical information.
For preparation of platelet poor plasma and calculations for the collection of sodium citrate tubes from individuals with elevated Hct, refer to Quest Diagnostics Nichols Institute Directory of Services under Specimen Collection section, Coagulation Testing, for further information on specimen processing.
Specimens must remain frozen during storage and shipment. All requests for coagulation assays should include a brief patient history and other pertinent clinical information.
Transport Container
Plastic screw-cap vial(s)
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 14 days
Refrigerated: Unacceptable
Frozen: 14 days
Methodology
Clotting Assay • Immunoturbidimetric • Platelet Agglutination • Photo/Optical • Photometric Clot Detection
Setup Schedule
Set up and Report available: Varies with assay
Reference Range
See Laboratory Report
Clinical Significance
This profile examines the most common causes of
coagulation-associated menorrhagia: von Willebrand's
disease, factor VIII deficiency (Hemophilia A carrier),
and factor XI deficiency. When all of these tests are
normal and the patient presents with spontaneous
ecchymoses and mucous membrane bleeding, a platelet
dysfunction (inherited or acquired) should be considered.
coagulation-associated menorrhagia: von Willebrand's
disease, factor VIII deficiency (Hemophilia A carrier),
and factor XI deficiency. When all of these tests are
normal and the patient presents with spontaneous
ecchymoses and mucous membrane bleeding, a platelet
dysfunction (inherited or acquired) should be considered.
