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Cortisol, Free, 24-Hour Urine with Creatinine, LC/MS/MS
Test Code11280
CPT Codes
82530
Preferred Specimen
2 mL aliquot of an unpreserved 24-hour urine submitted in a plastic, leak-proof container
Minimum Volume
0.5 mL
Other Acceptable Specimens
Aliquot of a preserved 24-hour urine preserved in 25 mL 6N HCl, or 10 mL concentrated glacial acetic acid, or 10 grams boric acid
Instructions
Collect 24-hour urine without preservative (preferred). Record 24-hour urine volume on test request form and urine vial.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 14 days
Refrigerated: 21 days
Frozen: 3 months
Refrigerated: 21 days
Frozen: 3 months
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Setup Schedule
Set up: Mon-Fri; Report available: 2-6 days
Reference Range
See Laboratory Report
Clinical Significance
Urinary Free Cortisol is useful in the detection of patients with Cushing's syndrome for whom Free Cortisol concentrations are elevated.
