D-Dimer, Quantitative

Test Code
10142


CPT Codes
85379<br /> Limited Access Code

Preferred Specimen
1 mL plasma collected from 3.2% sodium citrate (light blue-top) tube


Minimum Volume
0.5 mL


Instructions
Platelet poor plasma: Centrifuge light blue-top tube 15 minutes at approximately 1500g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/ platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL). Freeze immediately and ship on dry ice.


Transport Container
Plastic vial


Transport Temperature
Frozen (-70° C)


Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen (-70° C): 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gross lipemia • Clotted specimen • Improper blood to citrate ratio • Plasma received room temperature • Plasma received refrigerated


Methodology
Immunoturbidimetric

Setup Schedule
Set up: Tues-Sat; Report available: Next day


Reference Range
< 0.50 mcg/mL FEU


Clinical Significance
D-Dimer is one of the measurable by-products of activation of the fibrinolytic system. Quantitation of D-Dimer assesses fibrinolytic activation and intravascular thrombosis. D-Dimer is of particular value in excluding the diagnosis of venous thromboembolism among patients at high risk.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.