Cyclic AMP, Urine

Test Code

10126

CPT Codes
82030, 82570<br>Restricted Client Code

Preferred Specimen

10 mL random urine collected in a leak-proof urine container

Patient Preparation
PTH or ADH may be administered as a provocative test. No isotopes administered 48 hours prior to and during collection.

Minimum Volume

0.5 mL

Instructions

Transfer the urine into a LabCorp PP transpak frozen purple tube with screw cap (LabCorp No 49482).
Freeze immediately and maintain frozen until tested.
Freeze/thaw cycles: Stable x3

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 14 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Specimen not received frozen • Recently administered radioisotopes

Methodology
Radioimmunoassay

Setup Schedule

Set up: Varies; Report available: 5-7 days

Reference Range

See Laboratory Report

Clinical Significance

Differential diagnosis of hyperparathyroidism. In hyperparathyroidism there is increased cAMP in urine. Increased levels are also found in humoral hypercalcemia of malignancy and vitamin D deficiency. The plasma concentrations of immunoreactive parathyroid hormone-related protein correlate with levels of excreted cyclic AMP.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.