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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Alkaline Phosphatase, Bone Specific
Test Code29498
CPT Codes
84075
Preferred Specimen
1 mL serum
Minimum Volume
0.3 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 21 days
Refrigerated: 7 days
Frozen: 21 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Non-serum samples • Grossly icteric
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report available: 1-2 days
Reference Range
Adult Male | |
18-29 years | 8.4-29.3 mcg/L |
30-39 years | 7.7-21.3 mcg/L |
40-49 years | 7.0-18.3 mcg/L |
50-68 years | 7.6-14.9 mcg/L |
>68 years | Not established |
Adult Female | |
18-29 years | 4.7-17.8 mcg/L |
30-39 years | 5.3-19.5 mcg/L |
40-49 years | 5.0-18.8 mcg/L |
50-76 years | 5.6-29.0 mcg/L |
>76 years | Not established |
Premenopausal | |
35-45 years | 5.0-18.2 mcg/L |
Pediatric | Male (mcg/L) | Female (mcg/L) |
2-24 months** | 25.4-124.0 | 25.4-124.0 |
25 months-5 years | Not established | Not established |
6-9 years | 41.0-134.6 | 41.0-134.6 |
10-13 years | 43.8-177.4 | 24.2-154.2 |
14-17 years | 13.7-128.0 | 10.5-75.2 |
Clinical Significance
The bone-specific alkaline phosphatase (BSAP) assay provides a general index of bone formation and a specific index of total osteoblast activity. BSAP and osteocalcin are the most effective markers of bone formation and are particularly useful for monitoring bone formation therapies and antiresorptive therapies.