Varicella-Zoster Virus (VZV) Antibodies (Total, IgM), ACIF/IFA, CSF

Test Code

34972

CPT Codes
86787 (x2)

Includes

Varicella-Zoster Virus Antibody, ACIF, CSF
Varicella-Zoster Virus Antibody (IgM), IFA, CSF

Preferred Specimen

0.5 mL CSF collected in a sterile leak-proof container

Minimum Volume

0.2 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly icteric

Methodology

Anti-Complement Immunofluorescence (ACIF) • Indirect Fluorescent Antibody (IFA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Tues-Sat; Report available: 1-3 days

Reference Range

Varicella Zoster Virus Ab, Total ACIF, CSF	<1:2
Varicella Zoster Virus Ab (IgM), IFA, CSF	<1:1

Clinical Significance

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.