Maternal Cell Contamination Study, STR Analysis

Test Code

15896

CPT Codes
81265

Preferred Specimen

5 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

3 mL

Instructions

This code is only to be used when ordering code 15816, Sickle Cell Anemia, DNA Probe Analysis, Fetus, referred to Quest Diagnostics Nichols Institute, San Juan Capistrano. This test must be performed in order to rule out maternal contamination of the fetal sample.

This test is run in conjunction with a fetal specimen (Amniotic fluid or CVS). The assay cannot be run until fetal cultures are ready. The TAT is therefore dependent on the TAT of the fetal DNA test on the same patient.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 8 days
Refrigerated: 8 days
Frozen: unacceptable

Methodology
Multiplex Polymerase Chain Reaction • Fragment Analysis by Capillary Electrophoresis

FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.

Setup Schedule

See instructions

Reference Range

See Laboratory Report

Clinical Significance

Maternal Cell Contamination Study, STR Analysis, provides assurance that test results from fetal specimens are not influenced by contaminating maternal material. This test also allows for establishing the proper maternal-fetal relationship between specimens by using sophisticated analysis of 15 highly polymorphic STR loci.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.