Lactic Acid, CSF

Test Code
1659


CPT Codes
83605

Preferred Specimen
1 mL CSF collected in a sterile leak-proof container


Minimum Volume
0.5 mL


Instructions
If specimen is not clear or contains blood, centrifuge and separate supernatant fluid before freezing.

Note:
The assay manufacturer, Roche, notes that N-acetylcysteine, when administered in high concentrations (such as for treatment of acetaminophen overdose), can interfere with their assay for lactate (lactic acid), leading to falsely low results.


Transport Temperature
Frozen


Specimen Stability
Room temperature: 3 hours
Refrigerated: 24 hours
Frozen: 90 days


Methodology
Spectrophotometric

Setup Schedule
Monday-Friday All Shifts Sunday Night Report available: Next Day


Reference Range
Neonate 10-60 mg/dL
3-10 Days 10-40 mg/dL
11 Days-15 Years 10-25 mg/dL
Adult 10-22 mg/dL


Clinical Significance
Lactic Acid levels in CSF normally parallel blood levels. Increased CSF Lactic Acid levels occur in trauma, seizure, brain abscess, Multiple Sclerosis, and bacterial meningitis.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.