Coxsackie A Antibodies, CSF

Test Code
19895


CPT Codes
86658 (x6)

Includes
Coxsackie Antibodies A2, A4, A7, A9, A10, A16


Preferred Specimen
2 mL CSF collected in a sterile, leak-proof container


Minimum Volume
0.5 mL


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly icteric


Methodology
Complement Fixation (CF)

Setup Schedule
Set up: Tues-Sat; Report available: 2-5 days


Reference Range
Coxsackie A2 Ab <1:1 titer
Coxsackie A4 Ab <1:1 titer
Coxsackie A7 Ab <1:1 titer
Coxsackie A9 Ab <1:1 titer
Coxsackie A10 Ab <1:1 titer
Coxsackie A16 Ab <1:1 titer

Interpretive Criteria
<1:1 Antibody Not Detected
≥1:1 Antibody Detected


Clinical Significance
Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.