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Coxsackie A Antibodies, CSF
Test Code19895
CPT Codes
86658 (x6)
Includes
Coxsackie Antibodies A2, A4, A7, A9, A10, A16
Preferred Specimen
2 mL CSF collected in a sterile, leak-proof container
Minimum Volume
0.5 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly icteric
Methodology
Complement Fixation (CF)
Setup Schedule
Set up: Tues-Sat; Report available: 2-5 days
Reference Range
Coxsackie A2 Ab | <1:1 titer |
Coxsackie A4 Ab | <1:1 titer |
Coxsackie A7 Ab | <1:1 titer |
Coxsackie A9 Ab | <1:1 titer |
Coxsackie A10 Ab | <1:1 titer |
Coxsackie A16 Ab | <1:1 titer |
Interpretive Criteria
<1:1 | Antibody Not Detected |
≥1:1 | Antibody Detected |
Clinical Significance
Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.