Herpesvirus 8 IgG Antibody, IFA

Test Code

37959

CPT Codes
86790

Preferred Specimen

1 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.1 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Methodology
Immunoassay (IA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Thursday Morning Report available: Next Day

Reference Range

<1:20 titer

Interpretive Criteria

<1:20	Antibody Not Detected
≥1:20	Antibody Detected

Human herpesvirus-8 (HHV-8), also known as titer Kaposi's Sarcoma Herpesvirus (KSHV), is found in most cases of KS, including classic KS as well as AIDS-related KS. HHV-8 has also been detected in titer B-cell lymphomas in the abdominal cavity. IgG antibodies recognizing HHV-8 are found in >80% of titer KS patients and approximately 30% of titer HIV-seropositive individuals without KS, but less than 5% of healthy blood donors.

Clinical Significance

Human herpesvirus-8 (HHV-8), also known as Kaposi's Sarcoma Herpesvirus (KSHV), is found in most cases of Kaposi's Sarcoma (KS), including classic KS as well as AIDS-related KS. HHV-8 has also been detected in B-cell lymphomas in the abdominal cavity. IgG antibodies recognizing HHV-8 are found in >80% of KS patients and approximately 30% of HIV-seropositive individuals without KS, but less than 5% of healthy blood donors.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.