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Arbovirus Antibody (IgG) Panel, IFA, Serum
Test Code961
CPT Codes
86651, 86652, 86653, 86654
Includes
California Encephalitis, Eastern Equine Encephalitis, St. Louis Encephalitis, Western Equine Encephalitis
Preferred Specimen
1 mL serum collected in a serum separator tube (SST)
Minimum Volume
0.1 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric
Methodology
Immunofluorescence Assay (IFA)
Setup Schedule
Monday-Sunday Afternoon Report available: Next Day
Limitations
False-positive results may be produced if the patient has been immunized against yellow fever or if the patient has had previous infections that produce similar, cross-reacting antibodies.
Reference Range
<1:16
Clinical Significance
Human infections caused by arboviruses are seasonal, from mid-summer to late summer. Typical geographic distributions are: Eastern Equine Encephalitis virus from New England to Texas, California Encephalitis virus in the north central states, St. Louis Encephalitis virus throughout the southern, south-western, and west central states, and Western Equine Encephalitis virus throughout the western states.