Arbovirus Antibodies (IgG, IgM), IFA, Serum

Test Code
34980


CPT Codes
86651 (x2), 86652 (x2), 86653 (x2), 86654 (x2)

Includes
California Encephalitis (IgG, IgM),  Eastern Equine Encephalitis (IgG, IgM), St. Louis Encephalitis (IgG, IgM), Western Equine Encephalitis (IgG, IgM)


Preferred Specimen
1 mL serum collected in a red-top tube (no gel)


Minimum Volume
0.2 mL


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Icteric • Lipemic samples


Methodology
Immunofluorescence Assay (IFA)

Setup Schedule
Monday-Friday Morning
Report available: 3 Days


Limitations
False-positive results may be produced if the patient has been immunized against yellow fever or if the patient has had previous infections that produce similar, cross-reacting antibodies.


Reference Range
See individual tests


Clinical Significance
Serum is tested against antigens of California Encephalitis (La Crosse), Eastern Equine Encephalitis, St. Louis Encephalitis and Western Equine Encephalitis viruses. IgG titers >=1:16 suggest exposure, while the presence of IgM indicates recent infection. Incidence is seasonal from mid- to late-summer (July-October).




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.