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Post-Transplant, Varicella-Zoster Virus DNA, Real-Time PCR, CSF
Test Code18148
CPT Codes
87799
Preferred Specimen
1 mL CSF collected in a sterile plastic leak-proof container
Minimum Volume
0.5 mL
Instructions
For Shipper collection please see detailed instructions in Test Resources.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Methodology
Real-Time Polymerase Chain Reaction
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Monday-Sunday Morning
Report available: Next Day
Report available: Next Day
Reference Range
| VZV DNA, QN PCR | Not Detected (copies/mL) |
| VZV DNA, QN PCR | Not Detected (Log copies/mL) |
Clinical Significance
Varicella-Zoster virus (VZV) is a member of the Herpesviridae family that causes chickenpox as a primary infection and can reactivate later in life as herpes zoster or shingles. VZV infection in immunocompromised individuals often leads to a progressive disease state involving multiple organs. The detection of Varicella-Zoster Virus (VZV) DNA is based upon the real-time amplification and detection of specific VZV genomic DNA sequences by PCR from total DNA extracted from the specimen. Reportable range is 500 to 2,000,000 copies/mL (2.70 to 6.30 Log copies/mL).
