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Post-Transplant, Herpesvirus 8 DNA, Real-Time PCR, Plasma
Test Code18130
CPT Codes
87799
Preferred Specimen
1 mL plasma collected in an EDTA (lavender-top) tube
Minimum Volume
0.5 mL
Instructions
For Shipper collection please see detailed instructions in Test Resources
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Samples collected in sodium or lithium heparin • Unspun PPT tube
Methodology
Real-Time Polymerase Chain Reaction
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Daily; Report available: 1 day
Reference Range
| Herpesvirus 8 DNA, QN PCR | Not Detected (copies/mL) |
| Herpesvirus 8 DNA, QN PCR | Not Detected (Log copies/mL) |
Clinical Significance
Human herpesvirus-8 (HHV-8) is associated with the development of all forms of Kaposi's sarcoma, as well as with some other rare lymphoproliferative diseases, such as primary effusion lymphoma and multicentric Castleman's disease. Quantitative PCR may be used to monitor the level of viremia in a patient, often in the context of therapy. Reportable range is 1,000 to 10,000,000 copies/mL (3.00 to 7.00 Log copies/mL).
