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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Chlamydia/Neisseria gonorrhoeae RNA, TMA with Reflex to Alternate Target, Urogenital
Test Code91773
CPT Codes
87491, 87591
Includes
Chlamydia trachomatis RNA, TMA, Urogenital
Neisseria gonorrhoeae RNA, TMA, Urogenital
If Chlamydia trachomatis RNA, TMA, Urogenital is Detected, then Chlamydia trachomatis, TMA (Alternate Target), Urogenital will be performed at an additional charge (CPT code(s): 87491).
If Neisseria gonorrhoeae RNA, TMA, Urogenital is Detected, then Neisseria gonorrhoeae, TMA (Alternate Target), Urogenital will be performed at an additional charge (CPT code(s): 87591).
Neisseria gonorrhoeae RNA, TMA, Urogenital
If Chlamydia trachomatis RNA, TMA, Urogenital is Detected, then Chlamydia trachomatis, TMA (Alternate Target), Urogenital will be performed at an additional charge (CPT code(s): 87491).
If Neisseria gonorrhoeae RNA, TMA, Urogenital is Detected, then Neisseria gonorrhoeae, TMA (Alternate Target), Urogenital will be performed at an additional charge (CPT code(s): 87591).
Preferred Specimen
Vaginal, endocervical, or urethral swab submitted in an APTIMA® transport tube or
2 mL urine collected in an APTIMA® transport tube or
1 mL liquid cytology (PreservCyt®) preservative (ThinPrep®) submitted in an APTIMA® transport tube or
0.5 mL SurePath™ fluid submitted in an APTIMA® transport tube
2 mL urine collected in an APTIMA® transport tube or
1 mL liquid cytology (PreservCyt®) preservative (ThinPrep®) submitted in an APTIMA® transport tube or
0.5 mL SurePath™ fluid submitted in an APTIMA® transport tube
Minimum Volume
2 mL urine in Aptima® Transport • 1 mL PreservCyt® (ThinPrep®) in Aptima® Transfer Tube • 0.5 mL SurePath™ fluid in Aptima® Transfer Tube
Instructions
Vaginal swab: Follow instructions in the APTIMA® Vaginal Swab Collection or Multitest Collection Kit (orange label).
Endocervical or Urethral Swab: Follow instructions in the APTIMA® Unisex Swab Specimen Collection Kit (white label). In females, to ensure collection of cells infected with N. gonorrhoeae/C. trachomatis, columnar epithelial cells lining the endocervix should be obtained. Excess mucus should be removed prior to sampling.
Urine: Direct patient to provide a first-catch urine (a maximum of 20-30 mL of the initial urine stream) into a urine collection cup free of any preservatives. 2 mL of urine specimen must be transferred into the APTIMA® Specimen Transport within 24 hours of collection and before being assayed.
Use the tube provided in the urine specimen collection kit. The fluid (urine plus transport media) level in the urine transport tube must fall within the clear pane of the tube label.
Labs performing cytology: Aliquot ThinPrep® PreservCyt® solution before performance of liquid based cytology testing.
PreservCyt® ThinPrep® : Transfer 1 mL ThinPrep® PreservCyt® solution into APTIMA® Specimen Transfer Tube (green label) or APTIMA® Vaginal Collection or Multitest Collection Tube (orange label) or Unisex Swab Specimen Collection Kit (white label).
SurePath™: SurePath™ fluid must be transferred to APTIMA® tube within 4 days of collection. Transfer 0.5 mL SurePath™ solution into APTIMA® Specimen Transfer Tube (green label) or APTIMA® Vaginal Collection or Multitest Collection Tube (orange label) or Unisex Swab Specimen Collection Kit (white label).
Endocervical or Urethral Swab: Follow instructions in the APTIMA® Unisex Swab Specimen Collection Kit (white label). In females, to ensure collection of cells infected with N. gonorrhoeae/C. trachomatis, columnar epithelial cells lining the endocervix should be obtained. Excess mucus should be removed prior to sampling.
Urine: Direct patient to provide a first-catch urine (a maximum of 20-30 mL of the initial urine stream) into a urine collection cup free of any preservatives. 2 mL of urine specimen must be transferred into the APTIMA® Specimen Transport within 24 hours of collection and before being assayed.
Use the tube provided in the urine specimen collection kit. The fluid (urine plus transport media) level in the urine transport tube must fall within the clear pane of the tube label.
Labs performing cytology: Aliquot ThinPrep® PreservCyt® solution before performance of liquid based cytology testing.
PreservCyt® ThinPrep® : Transfer 1 mL ThinPrep® PreservCyt® solution into APTIMA® Specimen Transfer Tube (green label) or APTIMA® Vaginal Collection or Multitest Collection Tube (orange label) or Unisex Swab Specimen Collection Kit (white label).
SurePath™: SurePath™ fluid must be transferred to APTIMA® tube within 4 days of collection. Transfer 0.5 mL SurePath™ solution into APTIMA® Specimen Transfer Tube (green label) or APTIMA® Vaginal Collection or Multitest Collection Tube (orange label) or Unisex Swab Specimen Collection Kit (white label).
Transport Temperature
Room temperature
Specimen Stability
Swabs
Room temperature: 60 days
Refrigerated: 60 days
Frozen: 1 year
Urine
Room temperature: 30 days
Refrigerated: 30 days
Frozen: 1 year
Liquid cytology
Room temperature: 14 days
Refrigerated: 30 days
Frozen: 1 year
SurePath™
Room temperature: 14 days
Refrigerated: 14 days
Frozen: Unacceptable
Room temperature: 60 days
Refrigerated: 60 days
Frozen: 1 year
Urine
Room temperature: 30 days
Refrigerated: 30 days
Frozen: 1 year
Liquid cytology
Room temperature: 14 days
Refrigerated: 30 days
Frozen: 1 year
SurePath™
Room temperature: 14 days
Refrigerated: 14 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Transport tubes with 2 swabs • Transport tubes with Non-APTIMA® swabs • Swab transport tubes with no swab • Swab submitted in viral transport media • Urine samples where the fluid level is not between the black fill lines • PreservCyt® ThinPrep® material previously processed for cytology • PreservCyt® ThinPrep® with excess mucus
Methodology
Transcription-Mediated Amplification (TMA)
Setup Schedule
Set up: Mon-Sat; Report available: 3 days
Reference Range
| C. trachomatis RNA, TMA, Urogenital | Not detected |
| N. gonorrhoeae RNA, TMA, Urogenital | Not detected |
Clinical Significance
To screen for the infection with Neisseria gonorrhoeae and Chlamydia trachomatis in vaginal, endocervical and urethral swabs or urine from men and women.
