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C-Reactive Protein, High Sensitivity Profile #1
Test Code129402
CPT Codes
82465, 86141
Includes
Highly Sensitive C-Reactive Protein (CRP); Total Cholesterol
Preferred Specimen
2 mL serum collected in a serum seperator tube (SST®)
Minimum Volume
Serum: 1 mL
Plasma: 0.5 mL
Plasma: 0.5 mL
Other Acceptable Specimens
1 mL plasma collected in: sodium or lithium heparin (green-top) tube
Instructions
Centrifuge serum within 1 hour of collection, transfer to a sterile, plastic, screw-capped vial.
The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for... Cholesterol, Uric Acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.
The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for... Cholesterol, Uric Acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Serum
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 90 days
Plasma
Room temperature: 48 hours
Refrigerated: 48 hours
Frozen: 90 days
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 90 days
Plasma
Room temperature: 48 hours
Refrigerated: 48 hours
Frozen: 90 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Anticoagulants other than heparin • Moderate to gross icterus
Methodology
Enzymatic • Nephelometry
Setup Schedule
Set up: Sun-Fri; Report available: Same day
Reference Range
Interpretive report
