Hexosaminidase A and Total, Serum

Test Code

34841

CPT Codes
83080 (x2)

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Instructions

New York State clients: Informed consent is required. Please document on the test requisition or electronic order that a copy is on file.

If females wish screening for carrier status of hexosaminidase A deficiency, they must be tested prior to pregnancy. If the female is pregnant, we strongly suggest that her mate be tested for carrier status. Positive (or ambiguous) findings in the mate indicate a second order test on the female with leukocyte preparations. Refer to (Mayo code NAGR) Hexosaminidase A and Total, Leukocytes/Molecular Reflex or 34842 (Mayo code NAGW) Hexosaminidase A and Total Hexosaminidase, Leukocytes for carrier detection and diagnosis of Tay-Sachs disease.

Note: Serum assay results are often ambiguous on pregnant females and will not be run.

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days

Methodology
Heat Inactivation • Fluorometric • Automated

Setup Schedule

Set up: Varies; Report available: 8-15 days

Report Available

15 Days

Reference Range

Hexosaminidase Total
≤15 years	≥20 nmol/min/mL
≥16 years	10.4-23.8 nmol/min/mL
Hexosaminidase Percent A
≤15 years	20-90%
≥16 years	56-80%

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.