Drug Monitoring, Panel 7 with Confirmation, Urine

Test Code

39429

CPT Codes
80307

Includes

If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.

If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Initial screen of 6-Acetylmorphine, Alcohol Metabolites, Amphetamines, Barbiturates, Benzodiazepines, Marijuana Metabolite, Cocaine Metabolite, Methadone Metabolite, Opiates, Oxycodone drug classes. Specimen validity consisting of Creatinine, Oxidant, and pH testing.
If screen of drug class is positive, a confirmation of the drug class will be performed at an additional charge (CPT code(s): dependent upon the confirmed drug class).
Confirmation includes the following analytes within their associated drug class:
6-Acetylmorphine: 6-Acetylmorphine
Alcohol Metabolites: Ethyl Glucuronide (ETG), Ethyl Sulfate (ETS)
Amphetamines: Amphetamine, Methamphetamine
Barbiturates: Amobarbital, Butalbital, Pentobarbital, Phenobarbital, Secobarbital
Benzodiazepines: Alphahydroxyalprazolam, Alphahydroxymidazolam, Alphahydroxytriazolam, Aminoclonazepam, Hydroxyethylflurazepam, Lorazepam, Nordiazepam, Oxazepam, Temazepam
Marijuana Metabolite: Marijuana Metabolite
Cocaine Metabolite: Benzoylecgonine
Methadone Metabolite: EDDP, Methadone
Opiates: Codeine, Hydrocodone, Hydromorphone, Morphine, Norhydrocodone
Oxycodone: Noroxycodone, Oxycodone, Oxymorphone

Preferred Specimen

40 mL random urine collected in a clinical drug test transport vial

Minimum Volume

10 mL

Other Acceptable Specimens

Random urine collected in a sterile, leak-proof urine container

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 14 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Preserved samples

Methodology
Screen: Immunoassay (IA) • Confirmation: Mass Spectrometry (MS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Monday-Sunday Evening
Report available: 3 Days

Reference Range

See Laboratory Report

Clinical Significance

The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Presumptive positive screen results are reflexed to a more specific and sensitive liquid chromatography mass spectroscopy (LC/MS/MS) test. Therapeutic urine drug monitoring is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.