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Sertraline and Desmethylsertraline, Serum/Plasma
Test Code8871
CPT Codes
80299
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.4 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube or EDTA (pink-top) tube
Instructions
Promptly centrifuge and separate serum or plasma into a plastic, screw-capped vial, using approved guidelines.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 30 days
Frozen: 6 months
Refrigerated: 30 days
Frozen: 6 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Polymer gel separation tube (SST or PST)
Methodology
High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
Setup Schedule
Tuesday, Friday Morning
Report available: 4 Days
Report available: 4 Days
Reference Range
See Laboratory Report
Clinical Significance
Sertraline (Zoloft® ) is a psychiatric drug indicated for the treatment of major depression and obsessive-compulsive disorders. Its clinical efficacy is similar to that of the traditional antidepressants but are thought to be mediated through inhibition of serotonin reuptake in the brain.
