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Barbiturates, Urine
Test Code8416
CPT Codes
80345 (HCPCS: G0480)
Includes
Amobarbital, Butabarbital, Butalbital, Pentobarbital, Phenobarbital, Secobarbital
Preferred Specimen
10 mL urine collected in a plastic urine container, no preservative
Minimum Volume
5 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: Unacceptable
Refrigerated: 7 days
Frozen: Unacceptable
Methodology
Gas Chromatography/Mass Spectrometry (GC/MS)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Monday-Saturday Night Report available: 3 Days
Reference Range
See Laboratory Report
Clinical Significance
Barbiturates are used as hypnotics, sedatives and anesthetics and are readily absorbed from stomach. Duration of action of barbiturates, in therapeutic doses varies from: 8-16 hours (long acting, e.g., phenobarbital); 4-8 hours (intermediate acting, e.g., amobarbital); 3-6 hours (short acting, e.g., pentobarbital). Barbiturates may enhance other CNS depressants, such as ethanol, morphine derivatives, tranquilizers, and reserpine. Urine should only be used if blood cannot be obtained.