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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
FISH, Burkitt's/NHL/ALL, IGH/MYC, t(8;14)
Test Code17352
CPT Codes
88275, 88271 (x2)
Includes
Note: If results are not possible, the test order may be canceled and replaced with a Cytogenetics Communication.
Preferred Specimen
5 mL whole blood or 3 mL bone marrow collected in sodium heparin (green-top), sodium heparin (royal blue-top) or sodium heparin lead-free (tan-top) tube, or
5 X 5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution, or
Tissue in Formalin-fixed paraffin-embedded tissue
5 X 5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution, or
Tissue in Formalin-fixed paraffin-embedded tissue
Minimum Volume
1 mL whole blood or bone marrow
Instructions
Clinical history/reason for referral is required with test order. Prior therapy and transplant history should be provided with test order.
3-5 mL whole blood or 3 mL bone marrow collected in sodium heparin tube, 5 X 5 mm Fresh tissue in sterile container, Formalin Fixed Paraffin Embedded Tissue.
Specimen viability decreases during transit. Send specimen to testing laboratory for viability determination. Do not freeze. Do not reject.
3-5 mL whole blood or 3 mL bone marrow collected in sodium heparin tube, 5 X 5 mm Fresh tissue in sterile container, Formalin Fixed Paraffin Embedded Tissue.
Specimen viability decreases during transit. Send specimen to testing laboratory for viability determination. Do not freeze. Do not reject.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: See instructions
Refrigerated: See instructions
Frozen: See instructions
Refrigerated: See instructions
Frozen: See instructions
Methodology
Fluorescence in situ Hybridization (FISH)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Monday-Sunday Morning
Report available: 5 Days
Report available: 5 Days
Reference Range
See Laboratory Report
Clinical Significance
The translocation T(8;14)(Q24.1;Q32) is assayed by FISH with probes from the regions C-MYC (8Q24.1) and IGH (14Q32). This assay is useful to diagnose Burkitt's type lymphoma and some cases of Acute Lymphoblastic Leukemia.