FISH, Multiple Myeloma, IGH/MAF, t(14;16)

Test Code

16965

CPT Codes
88275, 88271 (x2)

Preferred Specimen

3 mL bone marrow collected in transport media

Minimum Volume

1 mL

Other Acceptable Specimens

Bone marrow collected in: sodium heparin (green-top), or sodium heparin (royal blue-top), or sodium heparin lead-free (tan-top) tube

Instructions

1-3 mL bone marrow in transport medium, bone marrow in sodium heparin tube (green-top) is preferred, (royal blue-top, tan-top) are acceptable. Ship at room temperature. Bone marrow transport medium is available upon request.

Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not reject.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: See instructions
Refrigerated: See instructions
Frozen: See instructions

Methodology
Fluorescence in situ Hybridization (FISH)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Daily; Report available: 6 days

Reference Range

See Laboratory Report

Clinical Significance

The IGH/MAF translocation, t(14;16), provides important prognostic information in patients with plasma cell myeloma.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.