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Drug Monitoring, Antidepressants, with Confirmation, Serum
Test Code94031
CPT Codes
80307
Includes
Amitriptyline, Amoxapine, Citalopram/Escitalopram, Clomipramine, Desipramine, Doxepin, Duloxetine, Fluoxetine, Fluvoxamine, Hydroxybupropion, Imipramine, Maprotiline, Mirtazapine, Nortriptyline, Paroxetine, Protriptyline, Sertraline, Trazodone, Trimipramine, Venlafaxine, Vilazodone, Vortioxetine
If screening drug class result is equal to or greater than the cutoff, then confirmation testing will be performed at an additional charge (CPT code(s): 80332, 80333, 80334, 80335, 80336, 80337, 80338 dependent on the confirmation(s) performed and the type of antidepressant).
If screening drug class result is equal to or greater than the cutoff, then confirmation testing will be performed at an additional charge (CPT code(s): 80332, 80333, 80334, 80335, 80336, 80337, 80338 dependent on the confirmation(s) performed and the type of antidepressant).
Preferred Specimen
0.5 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.25 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube or lithium heparin (green-top) tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 6 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Serum separator tube (SST)
Methodology
Chromatograpy/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat; Report available: 2-4 days
Reference Range
See Laboratory Report
Clinical Significance
Antidepressants are medications that can be used to treat mild, moderate, and severe depression. These medications may also be used to treat anxiety and eating disorders as well as pain (fibromyalgia and neuropathic). Antidepressant drug testing is intended for use in prescription adherence monitoring of patients prescribed antidepressant medications. Adherence monitoring requires prescribed drugs to be present, and the absence of non-prescribed drugs for these patient populations. Drug testing for prescription adherence can provide information for improvement of patient care. The results of drug testing can often prompt important clinical discussions with patients.
