|
|
| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
FISH, B-Cell Malignancy, IGH, 14q32 Rearrangement
Test Code17348
CPT Codes
88271 (x2), 88275
Includes
Note: If results are not possible, the test order may be canceled and replaced with code 39650 Cytogenetics Communication
Preferred Specimen
5 mL whole blood or 3 mL bone marrow collected in a sodium heparin (green-top) tube
5x5 mm fresh tissue collected in a culture transport media or formalin-fixed paraffin-embedded tissue
5x5 mm fresh tissue collected in a culture transport media or formalin-fixed paraffin-embedded tissue
Minimum Volume
1 mL
Other Acceptable Specimens
Whole blood or bone marrow collected in: Sodium heparin (royal blue-top) tube or sodium heparin lead-free (tan-top) tube • Fresh tissue: Culture transport media or sterile container with Hanks' or Ringers solution
Instructions
Clinical history and reason for referral are required with test order. Prior therapy and transplant history should be provided.
3-5 mL whole blood or 1-3 mL bone marrow collected in sodium heparin tube, 5x5 mm Fresh tissue in sterile container, Formalin Fixed Paraffin Embedded Tissue.
3-5 mL whole blood or 1-3 mL bone marrow collected in sodium heparin tube, 5x5 mm Fresh tissue in sterile container, Formalin Fixed Paraffin Embedded Tissue.
Transport Temperature
Room temperature
Specimen Stability
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not Reject.
Methodology
Fluorescence in situ Hybridization (FISH)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range
See Laboratory Report
Clinical Significance
The splitting of IgH region of chromosome 14q32 is frequently implicated in translocations seen in a variety of hematological malignancies of B-cell origin.
