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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Natural Killer Cells
Test Code37088
CPT Codes
86357
Includes
Absolute Lymphocytes
NK Cells CD3-CD16+CD56+ABS
CD3-/CD16+CD56+(%)
NK Cells CD3-CD16+CD56+ABS
CD3-/CD16+CD56+(%)
Preferred Specimen
5 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
0.5 mL
Instructions
Do not freeze. Do not transfer whole blood to M4. Submit EDTA tube at room temperature.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 72 hours
Refrigerated: Unacceptable
Frozen: Unacceptable
Refrigerated: Unacceptable
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Received refrigerated • Received frozen
Methodology
Flow Cytometry (FC)
Setup Schedule
Set up: Daily; Report available: 2-3 days
Reference Range
Absolute Lymphocytes | |
3 days | 2000-11500 cells/uL |
2 weeks | 2000-17000 cells/uL |
1 month | 2500-16500 cells/uL |
2 months | 3300-15000 cells/uL |
6 months | 4000-13500 cells/uL |
2 years | 4000-10500 cells/uL |
6 years | 2000-8000 cells/uL |
12 years | 1500-6500 cells/uL |
18 years | 1200-5200 cells/uL |
>18 years | 850-3900 cells/uL |
Natural Killer Cells CD3-CD16+CD56+ (ABS) | |
1 year | 160-930 cells/uL |
2 years | 95-620 cells/uL |
6 years | 60-540 cells/uL |
12 years | 70-500 cells/uL |
18 years | 60-430 cells/uL |
>18 years | 70-760 cells/uL |
CD3-/CD16+CD56+ (%) | |
1 year | 3-14 % |
2 years | 2-16 % |
6 years | 3-20 % |
12 years | 3-19 % |
18 years | 3-18 % |
>18 years | 4-25 % |
Clinical Significance
Low numbers of NK cells are found in individuals who are susceptible to viral infections, including cytomegalovirus and varicella.