Apolipoprotein B

Test Code

5224

CPT Codes
82172

Preferred Specimen

1 mL serum collected in a serum separator tube (SST)

Minimum Volume

0.5 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 10 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Grossly lipemic

Methodology
Immunoassay (IA)

Setup Schedule

Set up: Mon-Sat; Report available: 1-2 days

Reference Range

<90 mg/dL

Risk Category
Optimal	<90 mg/dL
Moderate	90-119 mg/dL
High	≥120 mg/dL

Cardiovascular event risk category cut points (optimal, moderate, high) are based on National Lipid Association recommendations- Jacobson TA et al. J of Clin Lipid. 2015; 9: 129-169 and Jellinger PS et al. Endocr Pract. 2017;23(Suppl 2):1-87.

Clinical Significance

Apolipoprotein B (APO B) has been reported to be a powerful indicator of CAD. In some patients with CAD, APO B is elevated even in the presence of normal LDL cholesterol.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.