Thrombin-Antithrombin (TAT) Complex

Test Code
10162


CPT Codes
83520

Preferred Specimen
1 mL platelet-poor plasma collected in a 3.2% sodium citrate (light blue-top) tube


Minimum Volume
0.5 mL


Instructions
Platelet poor plasma: Centrifuge light blue-top tube for 15 minutes at approximately 1500g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL). Freeze immediately and ship on dry ice.

Note on requisition if patient is on oral anticoagulant therapy.


Transport Temperature
Frozen


Specimen Stability
Room temperature: 4 hours
Refrigerated: 4 hours
Frozen: 30 days


Methodology
Enzyme Linked Immunosorbent Assay (ELISA)

Setup Schedule
Set up: Wed; Report available: 4 days


Reference Range
<4 mcg/L


Clinical Significance
Thrombin-Antithrombin (TAT) Complex is a parameter of coagulation and fibrinolysis. The Thrombin-Antithrombin Complex keeps clotting in check. Deficiencies may aid in understanding hypercoagulable states. Elevated concentrations have been associated with vascular complications associated with diabetes.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.