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Histoplasma Antibody, Complement Fixation, Serum
Test Code938
CPT Codes
86698 (x2)
Includes
Yeast Phase Antibody and Mycelial Phase Antibody
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Instructions
Please note: For CSF use test code 5297 or 5297X Histoplasma Antibody, Complement Fixation, CSF
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric
Methodology
Complement Fixation (CF)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Tuesday-Saturday Morning Report available: 2 Days
Reference Range
| Yeast Phase Ab | <1:8 titer |
| Mycelial Phase Ab | <1:8 titer |
Interpretive Criteria
| <1:8 | Antibody Not Detected |
| ≥1:8 | Antibody Detected |
Clinical Significance
This test is used for the diagnosis and prognosis of histoplasma infections. Titers ≥1:32 are highly suggestive of H. capsulatum infection. The CF test is more frequently positive with sera from chronic active pulmonary histoplasmosis than sera from primary active pulmonary disease.
