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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
ALK (D5F3) with Interpretation by Immunohistochemistry
Test Code36928
CPT Codes
88342
Preferred Specimen
Formalin fix (10% neutral buffered formalin) tumor tissue block, and paraffin-embedded tumor tissue block in tissue transport kit (ARUP supply #47808)
Other Acceptable Specimens
5 unstained (3-5 micron thick sections), positively charged slides submitted in a tissue transport kit (ARUP supply #47808)
Instructions
Protect paraffin block and/or slides from excessive heat. If sending precut slides, do not oven bake.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable
Refrigerated: Indefinitely
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Paraffin block with no tumor tissue remaining • Specimens fixed in any fixative other than 10 percent neutral buffered formalin
Methodology
Immunohistochemistry
Setup Schedule
Set up: Mon-Fri; Report available: 1-5 days
Reference Range
See Laboratory Report
Clinical Significance
Determine eligibility for tyrosine kinase inhibitor (TKI) therapy, primarily in individuals with pulmonary adenocarcinomas. Detects ALK fusion proteins.
