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Doxepin
Test Code826
CPT Codes
80299
Includes
Doxepin, Nordoxepin and Total
Preferred Specimen
3 mL serum collected in a red-top tube (no gel)
Minimum Volume
1.5 mL
Other Acceptable Specimens
Plasma collected in an: EDTA (lavender-top) tube, or sodium heparin (green-top) tube, or lithium heparin (green-top) tube
Instructions
Collect at steady-state trough concentration Specimen should be collected > 12 hours after dose.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Serum separator tubes (SST)
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat; Report available: Next day
Reference Range
Total | 110-250 mcg/L |
Clinical Significance
Doxepin is a tricyclic antidepressant. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.