|
|
| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Carbamazepine and Metabolite, Free
Test Code6071
CPT Codes
80157
Includes
Carbamazepine, Free and Carbamazepine Metabolite, Free
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
1.2 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube
Instructions
The use of Serum separator tube (SST) is not recommended.
Centrifuge and immediately separate serum or plasma specimens from the cells into clean, plastic, screw-capped vial(s).
Centrifuge and immediately separate serum or plasma specimens from the cells into clean, plastic, screw-capped vial(s).
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 10 months
Refrigerated: 14 days
Frozen: 10 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube (SST)
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat; Report available: 2 days
Reference Range
| Carbamazepine, Free | 1.0-3.0 mcg/mL |
| Carbamazepine Metabolite, Free | 0.1-1.0 mcg/mL |
Clinical Significance
Carbamazepine and its metabolite (10,11- Carbamazepine epoxide) are widely used for control of generalized tonic-clonic, partial-onset, complex and mixed seizure disorders. The metabolism of carbamazepine in epileptic patients has several different pathways that can be altered when the patient is comedicated with other anticonvulsants and, therefore, its therapeutic level should be monitored along with its metabolite in their free and protein-bound states.
