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IgG Synthesis Rate/Index, CSF
Test Code7558
CPT Codes
82040, 82042, 82784 (x2)
Includes
Albumin (CSF and Serum)
IgG (CSF and Serum)
IgG Index, CSF
Synthesis Rate IgG, CSF
IgG (CSF and Serum)
IgG Index, CSF
Synthesis Rate IgG, CSF
Preferred Specimen
2 mL CSF and 1 mL serum
Minimum Volume
1 mL CSF and 0.5 mL serum
Instructions
Both CSF & serum are required specimens. It is preferred that the collection date and time be the same for both; however, it is acceptable for them to be drawn within 48 hours of each other. If no serum is supplied, the client will be contacted to confirm the order.
CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.
Transport temperature: Refrigerate CSF specimens at 2-8°C in sterile, plastic CSF vial(s) and send refrigerated (cold packs) to the laboratory OR freeze CSF specimens at -20°C and send frozen samples to the laboratory on dry ice.
CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.
Transport temperature: Refrigerate CSF specimens at 2-8°C in sterile, plastic CSF vial(s) and send refrigerated (cold packs) to the laboratory OR freeze CSF specimens at -20°C and send frozen samples to the laboratory on dry ice.
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 8 hours
Refrigerated: 7 days
Frozen: 90 days
Refrigerated: 7 days
Frozen: 90 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Xanthochromia; RBCs • Hemolysis in CSF
Methodology
Nephelometry
Setup Schedule
Set up: Mon-Sat; Report available: 2-5 days
Reference Range
See Laboratory Report
Clinical Significance
The IgG Synthesis Rate/Index is useful in diagnosing and monitoring patients with multiple sclerosis and other inflammatory diseases involving the brain and meninges.
